j 113397 Search Results


j 113397  (Tocris)
93
Tocris j 113397
J 113397, supplied by Tocris, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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j 113397 - by Bioz Stars, 2026-08
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j-113397  (Banyu Pharmaceutical)
90
Banyu Pharmaceutical j-113397
J 113397, supplied by Banyu Pharmaceutical, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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orl1 antagonist j-113397  (Mitsubishi Pharma Deutschland)
90
Mitsubishi Pharma Deutschland orl1 antagonist j-113397
Binding affinity of W-212393 for <t> ORL1, </t> μ , δ , κ opioid receptors and serotonin transporter (SERT)
Orl1 Antagonist J 113397, supplied by Mitsubishi Pharma Deutschland, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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j 113397  (Biosynth Carbosynth)
90
Biosynth Carbosynth j 113397
Binding affinity of W-212393 for <t> ORL1, </t> μ , δ , κ opioid receptors and serotonin transporter (SERT)
J 113397, supplied by Biosynth Carbosynth, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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j-113397  (Tsukuba Research Laboratories)
90
Tsukuba Research Laboratories j-113397
Binding affinity of W-212393 for <t> ORL1, </t> μ , δ , κ opioid receptors and serotonin transporter (SERT)
J 113397, supplied by Tsukuba Research Laboratories, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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saturated structural congeners of j-113397  (Purdue Pharma)
90
Purdue Pharma saturated structural congeners of j-113397
Binding affinity of W-212393 for <t> ORL1, </t> μ , δ , κ opioid receptors and serotonin transporter (SERT)
Saturated Structural Congeners Of J 113397, supplied by Purdue Pharma, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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j-113397  (Merck KGaA)
90
Merck KGaA j-113397
Binding affinity of W-212393 for <t> ORL1, </t> μ , δ , κ opioid receptors and serotonin transporter (SERT)
J 113397, supplied by Merck KGaA, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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(±)-j 113397  (TargetMol)
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(±)-j 113397  (BOC Sciences)
N/A
(+/-)-J 113397 has been found to be a NOP receptor antagonist and could restrain nociceptin/orphanin FQ-induced hyperalgesia in the mouse tail-flick test.
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j-113397  (TargetMol)
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(±)-j 113397  (Aladdin Scientific Corporation)
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Image Search Results


Binding affinity of W-212393 for ORL1, μ , δ , κ opioid receptors and serotonin transporter (SERT)

Journal:

Article Title: Nonphotic entrainment of the circadian body temperature rhythm by the selective ORL1 receptor agonist W-212393 in rats

doi: 10.1038/sj.bjp.0706311

Figure Lengend Snippet: Binding affinity of W-212393 for ORL1, μ , δ , κ opioid receptors and serotonin transporter (SERT)

Article Snippet: Drugs and chemicals W-212393 ( ) and an ORL1 antagonist J-113397 ( Ozaki et al ., 2000 ) were synthesized at Mitsubishi Pharma Corporation (Japan).

Techniques: Binding Assay, Recombinant

Effects of N/OFQ and W-212393 on the spontaneous action potential firing of SCN neurons. (a) SCN slice placed on MED. (b) Representative trace of spontaneous firing activity recorded by the marked electrode (white square) in (a). Effect of N/OFQ (c) and W-212393 (d). N/OFQ and W-212393 were applied by bath perfusion for 10 min. Both N/OFQ and W-212393 significantly suppress the activity of spontaneously firing rat SCN neurons. The suppressive effects of N/OFQ and W-212393 did not recover after extensive washes for up to 40 min. (e) ORL1 receptor antagonist J-113397 (1 μM) prevented the reduction of the spontaneous firing rate by N/OFQ (100 nM) and W-212393 (100 nM). J-113397 was applied by bath perfusion 10 min before N/OFQ application. N/OFQ and W-212393 were applied by bath perfusion for 10 min with 20 min interval.

Journal:

Article Title: Nonphotic entrainment of the circadian body temperature rhythm by the selective ORL1 receptor agonist W-212393 in rats

doi: 10.1038/sj.bjp.0706311

Figure Lengend Snippet: Effects of N/OFQ and W-212393 on the spontaneous action potential firing of SCN neurons. (a) SCN slice placed on MED. (b) Representative trace of spontaneous firing activity recorded by the marked electrode (white square) in (a). Effect of N/OFQ (c) and W-212393 (d). N/OFQ and W-212393 were applied by bath perfusion for 10 min. Both N/OFQ and W-212393 significantly suppress the activity of spontaneously firing rat SCN neurons. The suppressive effects of N/OFQ and W-212393 did not recover after extensive washes for up to 40 min. (e) ORL1 receptor antagonist J-113397 (1 μM) prevented the reduction of the spontaneous firing rate by N/OFQ (100 nM) and W-212393 (100 nM). J-113397 was applied by bath perfusion 10 min before N/OFQ application. N/OFQ and W-212393 were applied by bath perfusion for 10 min with 20 min interval.

Article Snippet: Drugs and chemicals W-212393 ( ) and an ORL1 antagonist J-113397 ( Ozaki et al ., 2000 ) were synthesized at Mitsubishi Pharma Corporation (Japan).

Techniques: Activity Assay